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Depressed? Researchers identify new anti-depressant mechanisms, therapeutic approaches

Researchers at UT Southwestern Medical Center are making breakthroughs that could benefit people suffering from depression. A team of physician-scientists at UT Southwestern has identified a major mechanism by which ghrelin (a hormone with natural anti-depressant properties) works inside the brain. Simultaneously, the researchers identified a potentially powerful new treatment for depression in the form [...]

Protein Linked To Hunger Also Implicated In Alcoholism

Researchers at The Scripps Research Institute have found new links between a protein that controls our urge to eat and brain cells involved in the development of alcoholism. The discovery points to new possibilities for designing drugs to treat alcoholism and other addictions. The new study, published online ahead of print by the journal Neuropsychopharmacology, [...]

Low Ghrelin – Reducing Appetite At The Cost Of Increased Stress?

Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity — in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied as a treatment for obesity. However, many people eat as a way to relieve stress. [...]

If You Always Have Room For Dessert, Ghrelin May Be To Blame

A new study suggests that the appetite-inducing hormone ghrelin increases the incentive for humans to eat high-calorie foods, even on a full stomach. The results were reported at The Endocrine Society’s 94th Annual Meeting in Houston. In the study, rats lacking the ghrelin receptor gene ate less of a sweet treat after a full meal [...]