3 days popular7 days popular1 month popular3 months popular

Genetic mechanism driving obesity identified

Variation in DNA sequence increases fat storage A specific gene region has long been suspected of contributing to obesity in humans but the precise mechanisms behind this were previously unclear. Now, researchers at the Technical University of Munich (TUM), Massachusetts Institute of Technology (MIT), Harvard Medical School and other partners have been able to show [...]

Systematic review shows ‘smart drug’ modafinil does enhance cognition

The drug modafinil was developed to treat narcolepsy (excessive sleeping), but it is widely used off-licence as a ‘smart drug’ to promote cognitive enhancement, where qualities such as alertness and concentration are desired to assist someone with, for example, exam preparation. Past studies on sleep-deprived individuals have shown a strong positive effect of modafinil on [...]

Research from Harvard and Johns Hopkins shows surge in journal articles on yoga therapy

During the last 10 years, the number of articles in peer-reviewed journals worldwide about clinical trials of yoga therapy to alleviate disease-related symptoms increased 3-fold. This large-scale analysis of published research studies spanning 46 years, 29 countries, and more than 28,000 study participants is published in The Journal of Alternative and Complementary Medicine, a peer-reviewed [...]

Preserving photoreceptor cells following retinal injury

Vision researchers at Massachusetts Eye and Ear/Harvard Medical School (HMS) Department of Ophthalmology have taken a first step in solving a vexing problem: how to preserve photoreceptor cells and avoid irreversible vision loss in patients following retinal detachment. Left, an image of a human retina from a healthy individual. Right, a retinal image from a [...]

New techniques improve specificity of CRISPR/CAS9 genome editing tools

To overcome the off-target mutations that commonly occur with CRISPR/Cas9 genome editing methods, researchers at Harvard Medical School and Massachusetts General Hospital have developed two strategies that greatly improve the specificity of RNA-guided nucleases for the DNA region targeted to be cut and repaired. A description of these new techniques and their successful use to [...]