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Spray application of respiratory cells holds promise for tissue engineering

A new study showing the ability to apply a thin coating of viable respiratory epithelial cells to tissue engineered constructs using a commercially available spray device is especially promising for therapeutic approaches in development to repair or replace challenging structures such as trachea or bronchi. The effects of factors such as air pressure and nozzle [...]

New gene therapy method provides specific, safe control of therapeutic transgenes

Korean researchers have described a novel control system to regulate the expression of a therapeutic transgene by targeting the passenger strand of a microRNA (miR-122) linked to the transgene. The researchers report that a control system based on targeting the passenger strand of miR-122 rather than the guide strand can regulate expression of an exogenous, [...]

Biomaterial scaffold implanted after spinal cord injury promotes nerve regeneration

Researchers from the Mayo Clinic demonstrated that implantation of a biomaterial scaffold designed to bridge the lesion caused by a spinal cord injury creates a tissue environment more favorable for nerve regeneration. The desirable tissue reaction to the implant did not appear to depend on whether the scaffold was seeded with tissue-specific cells, according to [...]

Successful model for statewide collaborative initiative to reduce avoidable hospital readmissions

A statewide effort led by key stakeholders in South Carolina successfully organized and implemented an evidence-based initiative aimed at improving the quality of healthcare transitions after hospital discharge to prevent avoidable readmissions. This promising model for engaging healthcare partners statewide and accelerating adoption of care transitions strategies is described in an article in Population Health [...]

Data demonstrates long term effectiveness and safety of telescope implant for macular degeneration in patients 65 years and older

VisionCare Ophthalmic Technologies, Inc. a developer of advanced visual prosthetic devices for the treatment of age-related macular degeneration (AMD), has announced the publication of “Long-Term (60-month) Results for the Implantable Miniature Telescope: Efficacy and Safety Outcomes Stratified by Age in Patients with End-Stage Age-Related Macular Degeneration” in Clinical Ophthalmology. The 5-year data show substantial retention [...]