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Lipid enzyme heightens insulin sensitivity, potential therapy to treat Type 2 diabetes

Reducing high concentrations of a fatty molecule that is commonly found in people with diabetes and nonalcoholic fatty liver disease rapidly improves insulin sensitivity, UT Southwestern Medical Center diabetes researchers have found. Insulin is a crucial hormone that helps the body convert sugar into energy, absorb nutrients, and reduce the storage of sugars as fat. [...]

Obesity: small intestine contributes to chronic inflammation

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals (AP-HP) have now shown that severe obesity is accompanied by inflammation of the small intestine and enhanced immune response in that region. [...]

Study shows that use of statins increases risk of developing diabetes by 46%, even after adjustment for confounding factors

Researchers investigate the effects of statin treatment on the risk of type 2 diabetes and deterioration of blood sugar control New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that use of statins is associated with a 46% increase in the risk of developing diabetes, even after [...]

Insulin resistance linked to a human gene variant

Insulin resistance is a risk factor for developing both type 2 diabetes and cardiovascular disease. Almost one third of the U.S. population has some degree of insulin resistance, though it is undiagnosed in many of these individuals. Obesity is associated with reduced insulin sensitivity and the development of insulin resistance. However, recent large-scale genetic studies [...]

Women retain insulin sensitivity better than men

It’s long been known that obese men are more likely to develop type two diabetes than obese women, but researchers at McMaster University have discovered it may be related to a difference between the sexes in the activity of a protein in the muscle. As people become overweight, their skeletal muscle develops insulin resistance that [...]