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Miriam Hospital researchers find topical TXA in total joint replacement lowers blood transfusion use

Standardized protocol for tranexamic acid shows topical use also reduces patient length of stay, health care costs Orthopedic surgeons from The Miriam Hospital have conducted a cost-benefit analysis of topical tranexamic acid (TXA) in primary total hip and knee arthroplasty patients that revealed a 12 percent transfusion rate reduction – from 17.5 percent to 5.5 [...]

In-flight blood transfusions increase survival rates and improve trauma patient outcomes

Largest civilian study published in Journal of American College of Surgeons confirms effectiveness of transfusion protocol used in Iraq and Afghanistan Air-lifted trauma victims who received blood transfusions in the helicopter before arriving at a trauma center had higher one-day survival rates and less chance of shock than air-lifted patients who did not receive blood [...]

FDA approves pathogen reduction system to treat platelets

The U.S. Food and Drug Administration has approved the Intercept Blood System for platelets, the first pathogen reduction system to treat single donor apheresis platelets. The system is for use by blood establishments that collect and manufacture blood and blood components to prepare pathogen reduced platelets for transfusion to reduce the risk of transfusion-transmitted infections. [...]

Researchers develop novel molecular blood group typing technique

Scientists in France have designed a new system for molecular blood group typing that offers blood banks the possibility of extensive screening of blood donors at a relatively low cost. Their approach is described in The Journal of Molecular Diagnostics. Although blood transfusion is generally safe, alloimmunization (when an antibody is formed in response to [...]

Blood transfusion for patients undergoing PCI associated with increased risk of in-hospital cardiac event

In an analysis that included more than two million patients who underwent a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), there was considerable variation in red blood cell transfusion practices among hospitals across the U.S., and receiving a transfusion was associated with an increased [...]