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Finding a way forward in the fight against prion disease

UAlberta study finds bile acids may prolong survival in models of prion disease For much of her adult life Valerie Sim has been fascinated by a disease very few in the world can claim to even begin to understand. Sim is one of Canada’s foremost authorities on prion disease–more commonly known as bovine spongiform encephalopathy, [...]

Potential new class of drug to fight diabetes

The growing epidemic of obesity across the world is associated with an equivalent increase in type-2 diabetes, which results from the body’s ineffective use of insulin. Obese people often develop inflammation in their fat tissue, which, in turn, can reduce the sensitivity of fat cells to insulin, resulting in type-2 diabetes. EPFL scientists, working with [...]

Bile acids could be a new target for treating obesity and diabetes

Bariatric surgery has positive effects not only on weight loss but also on diabetes and heart disease. Researchers at the Sahlgrenska Academy and University of Cincinnati have shown that the health benefits are not caused by a reduction in the stomach size but by increased levels of bile acids in the blood. These findings, reported [...]

Bile acids could be a new target for treating obesity and diabetes

Bariatric surgery has positive effects not only on weight loss but also on diabetes and heart disease. Researchers at the Sahlgrenska Academy and University of Cincinnati have shown that the health benefits are not caused by a reduction in the stomach size but by increased levels of bile acids in the blood. These findings, reported [...]

Bile Diversion A Possible Alternative To Bariatric Weight Loss Surgery

An experimental procedure successfully tested in obese laboratory rats may provide a less-invasive alternative to bariatric weight-loss surgery, researchers report online in Endocrinology. Scientists at Cincinnati Children’s Hospital Medical Center used a catheter to re-direct the flow of bile from the bile duct into the small intestine, producing the same metabolic and weight-loss benefits as [...]