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Genetically predicted higher BP linked to antihypertensive use and lower Alzheimer’s risk

Genetic variants that predict higher systolic blood pressure (SBP) are associated with a higher probability of taking antihypertensive medication and with decreased risk of Alzheimer disease (AD), according to a study published this week in PLOS Medicine. The study, conducted by Robert Scott of the MRC Epidemiology Unit, University of Cambridge, UK, Soren Ostergaard, (Aarhus [...]

Global collaboration announced as G7 leaders meet to drive progress on dementia

Three leading research funders from the UK and North America have joined forces to launch a new global initiative called MEND or, MEchanisms of cellular death in NeuroDegeneration, with a fund of $1.25m USD (£820,000/$1.56CDN) for targeted research into brain diseases that cause dementia, such as Alzheimer’s. Alzheimer’s Research UK, the Alzheimer’s Association based in [...]

Scientists look to heart disease and stroke-related disorders for clues to preventing and treating Alzheimer’s

A growing body of research suggests that the most common cause of dementia in older people is a mix of vascular and Alzheimer’s-related brain abnormalities, and that approximately half of people who die with Alzheimer’s also have evidence of strokes in their brains. Furthermore, when strokes and hallmark Alzheimer’s plaques and tangles are combined, it [...]

Clues to treating Alzheimer’s may be provided by heart disease and strokes

A growing body of research suggests that the most common cause of dementia in older people is a mix of vascular and Alzheimer’s-related brain abnormalities, and that approximately half of people who die with Alzheimer’s also have evidence of strokes in their brains. Furthermore, when strokes and hallmark Alzheimer’s plaques and tangles are combined, it [...]

Genetic variant linked to better memory performance

People with a newly identified genetic variant perform better on certain types of memory tests, a discovery that may point the way to new treatments for the memory impairments caused by Alzheimer’s disease or other age-associated conditions. In what the international research team is calling the largest study to date of human memory, an analysis [...]