The ductal carcinoma in situ (DCIS) Score quantifies the risk of ipsilateral breast event (IBE) and invasive IBE risk, complements both traditional clinical and pathologic factors, and helps provide a new clinical tool to improve the process of selecting individualized treatment for women with DCIS who meet the criteria, according to a study published in [...]
A study from the Cancer Genome Atlas Research Network, led by the National Cancer Institute and the National Human Genome Research Institute, report that mutations discovered in endometrial cancer genes may directly impact treatment plans for women with aggressive endometrial cancer, as well as the classification of endometrial cancer tumors. The study was published in [...]
Cancer cells that can break out of a tumor and invade other organs are more aggressive and nimble than nonmalignant cells, according to a new multi-institutional nationwide study. These cells exert greater force on their environment and can more easily maneuver small spaces. The researchers report in the journal Scientific Reports that a systematic comparison [...]
Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the National Institutes of Health (NIH). Their experiments, reported in Scientific Reports, also show that the process doesn’t require other kinds of [...]
Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from the National Cancer Institute in Bethesda, USA, and Didier Picard, from the University of Geneva (UNIGE), Switzerland, this outlook is now [...]
