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Study finds PrEP use feasible among high-risk groups in US community settings

A majority of men who have sex with men (MSM) and transgender women (TGW) at high risk for HIV infection took anti-HIV medication for pre-exposure prophylaxis (PrEP), most of the time, in a multi-site U.S. study examining use of this HIV prevention strategy outside of a clinical trial. The study, called the PrEP Demo Project, [...]

UNMC/Nebraska Medicine to be part of Liberia-U.S. clinical research partnership to test Ebola treatments

In partnership with the Liberian government, the National Institute of Allergy and Infectious Diseases (NIAID) today launched a clinical trial to obtain safety and efficacy data on the investigational drug ZMapp as a treatment for Ebola virus disease. The study, which will be conducted in Liberia and the United States, is a randomized controlled trial [...]

RX approach discovered that reduces herpes virus infection

A multi-institutional study reports an effective treatment approach to inhibit and keep latent viruses like herpes simplex from reactivating and causing disease. The work, whose lead author is the late James Hill, PhD, LSU Health New Orleans Professor and Director of Pharmacology and Infectious Disease at the LSU Eye Center, is published in the journal [...]

Some flu viruses potentially more dangerous than others

Certain subtypes of avian influenza viruses have the potential to cause more severe disease in humans than other avian influenza subtypes and should be monitored carefully to prevent spread of disease, according to a study published this week in mBio®, the online open-access journal of the American Society for Microbiology. The work, directed by researchers [...]

New methods to predict gene and protein functions lead to significant advance in malaria research

Researchers led by Baylor College of Medicine have developed a new computational method to study the function of disease-causing genes, starting with an important new discovery about a gene associated with malaria – one of the biggest global health burdens. The work published in the current issue of the journal Cell includes collaborators comprised of [...]