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New insight into inflammatory bowel disease may lead to better treatments

Inflammatory bowel disease (IBD) afflicts 1.6 million people in the United States, causing abdominal pain, diarrhea, constipation, rectal bleeding and other potentially debilitating symptoms. Marked by yellow tags, the tiny particles released by this bacterium may help initiate inflammatory bowel disease, according to new research from Washington University School of Medicine in St. Louis. Credit: [...]

Ease of weight loss influenced by individual biology

NIH study finds varied responses to calorie restriction in obese adults For the first time in a lab, researchers at the National Institutes of Health found evidence supporting the commonly held belief that people with certain physiologies lose less weight than others when limiting calories. Study results published in Diabetes. Researchers at the Phoenix Epidemiology [...]

Scientists coax stem cells to form 3-D mini lungs

Human lung organoids will help scientists learn more about lung diseases, test new drugs Scientists, led by the University of Michigan Medical School, coax stem cells to form mini lungs, 3-D structures that mimic human lungs and survived in the lab for 100 days. Credit: University of Michigan Health System __SOURCEFROM__ The research has gained [...]

Penn vet team points to new colon cancer culprit

Colon cancer is a heavily studied disease — and for good reason. It is one of the leading causes of cancer-related deaths worldwide, and its numbers are on the rise, from 500,000 deaths in 1990 to 700,000 in 2010. Msi2 (stained red) is broadly expressed in intestinal tumors that result from loss of APC. Penn [...]

Circadian clock-Angelman syndrome link established

Link could provide quickest way to determine effectiveness of experimental AS treatments Monitoring participants’ biological clocks may be the quickest way to determine the effectiveness of experimental drugs currently under development to treat Angelman syndrome: a debilitating genetic disorder that occurs in more than one in every 15,000 live births. This is a five-month-old baby [...]