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Lipid enzyme heightens insulin sensitivity, potential therapy to treat Type 2 diabetes

Reducing high concentrations of a fatty molecule that is commonly found in people with diabetes and nonalcoholic fatty liver disease rapidly improves insulin sensitivity, UT Southwestern Medical Center diabetes researchers have found. Insulin is a crucial hormone that helps the body convert sugar into energy, absorb nutrients, and reduce the storage of sugars as fat. [...]

Mistletoe could fight obesity-related liver disease

Mistletoe hanging in doorways announces that the holidays are just around the corner. For some people, however, the symbolic plant might one day represent more than a kiss at Christmas time: It may mean better liver health. Researchers have found that a compound produced by a particular variety of the plant can help fight obesity-related [...]

Nonalcoholic fatty liver disease promoted by microbial-induced pathway

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder and affects approximately 1 billion people worldwide. It is not clear how this disease develops, but recent studies suggest that the bacterial population in the gut influences NAFLD. A new study in the Journal of Clinical Investigation provides a link between molecular signaling pathways [...]

New treatments for liver diseases

Cirrhosis and nonalcoholic fatty liver disease (NAFLD) are two serious liver conditions with limited pharmacological treatments. The December issues of AGA’s journals — Clinical Gastroenterology and Hepatology and Gastroenterology — highlight important updates into treatments for these two debilitating diseases. Promising Probiotic for Liver Disease A study published in em>Gastroenterology1 found that, over a six-month [...]

Prevention of fatty liver disease in mouse model

Studying mice, researchers have found a way to prevent nonalcoholic fatty liver disease, the most common cause of chronic liver disease worldwide. Blocking a path that delivers dietary fructose to the liver prevented mice from developing the condition, according to investigators at Washington University School of Medicine in St. Louis. The study appears in a [...]