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Cholecystokinin octapeptide antagonizes apoptosis in retinal pigment epithelial cells

Oxidative stress may cause retinal pigment epithelial (RPE) cell apoptosis. Nitric oxide and superoxide react to produce peroxynitrite, which, along with its derivatives, are strong oxidants. Cholecystokinin octapeptide-8 (CCK-8) can protect cholinergic neurons against basal forebrain lesion caused by brain injury. The research team at Hebei Province People’s Hospital, China led by Dr. Yuan Liu [...]