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First ‘targeted’ treatment for small cell lung cancer shows promise

Small cell lung cancer (SCLC) is an aggressive disease that is difficult to treat and is frequently only diagnosed when it has spread to other parts of the body (metastasised). Five-year survival rates in SCLC, which accounts for about 14% of all lung cancers, are very low, at only six percent. But today US researchers [...]

Future medicinal chemistry shines the spotlight on schistosomiasis

In a special free issue of Future Medicinal Chemistry, leading experts explore current and potential new treatment options for the deadly neglected tropical disease schistosomiasis. The journal is published by Future Science Group. In this issue, experts discuss drug discovery and development advances towards addressing schistosomiasis, also known as bilharzia, a disease caused by parasitic [...]

ASCO: JAK2 inhibitor ruxolitinib has promising efficacy in CMML patients

Chronic myelomonocytic leukemia (CMML) is a rare type of myelodysplastic, myeloproliferative neoplasm characterized by increased numbers of peripheral monocytes and less than 20 percent blasts. CMML has few treatment options and patients only survive on average for 12 to 24 months. Preclinical studies suggest that JAK2 inhibitors may be an effective treatment option for CMML. [...]

New biosensing platform could quickly and accurately diagnose disease and monitor treatment remotely

In much the same way that glucometers and pregnancy tests have revolutionized in-home diagnostic testing, researchers from Florida Atlantic University and collaborators have identified a new biosensing platform that could be used to remotely detect and determine treatment options for HIV, E-coli, Staphylococcus aureas and other bacteria. Using a drop of blood from a fingerprick, [...]

NTU finds new treatment options for colon cancer

Existing chemo drug reduced colon tumor growth by half This is NTU scientist Dr. Parag Kundu in his lab, with the images of mice colon tumors on his laptop. Credit: NTU Singapore __SOURCEFROM__ Nanyang Technological University