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Bionic liver micro-organs explain off-target toxicity of acetaminophen (Tylenol)

Israeli-German partnership aims to replace animal experiments with advanced liver-on-chip devices This image shows the Hebrew University liver-on-chip device. Credit: (Photo credit: Yaakov Nahmias / Hebrew University)

Israeli-German partnership aims to replace animal experiments with advanced liver-on-chip devices

Safety evaluation is a critical part of drug and cosmetic development. In recent years there is a growing understanding that animal experiments fail to predict the human response, necessitating the development of alternative models to predict drug toxicity. The recent tightening of European regulations preventing the cosmetic industry from using animals in research and development, [...]