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RTOG 0537 shows acupuncture-like ENS may provide relief for radiation-induced dry mouth

Phase III results evaluated ENS and current standard treatment, pilocarpine Phase III results of Radiation Therapy Oncology Group (RTOG) 0537 indicate that acupuncture-like, transcutaneous electrical nerve stimulation (ALTENS) may be equally effective as pilocarpine, the current prescription medication in a pill, to treat radiation-induced xerostomia (dry mouth), according to a study published in the June [...]

Erythropoietin combined with radiation therapy does not improve local-regional control in anemic patients with head and neck cancer

Long-term analysis of Radiation Therapy Oncology Group (RTOG) 9903 demonstrates that the addition of erythropoietin (EPO) did not improve local-regional control for anemic patients with head and neck squamous cell carcinoma (HNSCCa) who receive radiation therapy or chemoradiation, according to a study published in the International Journal of Radiation Oncology * Biology * Physics (Red [...]

Clinical trial suggests combination therapy is best for low-grade brain tumors

New clinical-trial findings provide further evidence that combining chemotherapy with radiation therapy is the best treatment for people with a low-grade form of brain cancer. The findings come from a phase II study co-led by a researcher at Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research [...]

Double the survival rate for HPV-positive OPSCC patients compared to HPV-negative patients

A retrospective analysis of oropharyngeal patients with recurrence of disease after primary therapy in the Radiation Therapy Oncology Group (RTOG) studies 0129 or 0522 found that HPV-positive patients had a higher overall survival (OS) rate than HPV-negative patients (at two years post-treatment, 54.6 percent vs. 27.6 percent, respectively), according to research presented at the 2014 [...]

In intermediate risk prostate cancer, fewer weeks of hormone therapy before radiation reduces side effects

A shorter course of androgen suppression therapy prior to radiation therapy, when compared to a longer course of androgen suppression therapy, yields favorable outcomes and fewer adverse effects for intermediate-risk prostate cancer patients, according to research presented today at the American Society for Radiation Oncology’s (ASTRO) 55th Annual Meeting. The study confirmed a disease-specific-survival (DSS) [...]