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A risk score for chronic kidney disease can inform choice of HIV medications

Both traditional and HIV-related risk factors can predict the likelihood of developing chronic kidney disease (CKD), according to a study published in PLOS Medicine. In the study, Amanda Mocroft, of University College London, United Kingdom, and colleagues developed and validated a risk score model that can help inform choices among antiretroviral drugs for patients with [...]

Potential biomarker identified for Alzheimer’s disease

Researchers from Boston University School of Medicine (BUSM) report variants in a new gene, PLXNA4, which may increase the risk of developing Alzheimer’s disease (AD). The discovery of this novel genetic association may lead to new drug treatment options that target PLXNA4 specifically. These findings appear in the Annals of Neurology. AD is the most [...]

Patients With Epilepsy Appear To Present Earlier With Mild Cognitive Impairment, Alzheimer Disease

Patients with epilepsy who had amnestic mild cognitive impairment (aMCI) or Alzheimer disease (AD) presented earlier with cognitive decline than patients who did not have epilepsy, according to a report published by JAMA Neurology, a JAMA Network publication. AD increases a patient’s risk of risk of seizures, and patients with AD and seizure disorders have [...]

Alzheimer’s Scans Using Florbetapir Can Guide Treatment And Further Testing

A test to detect brain amyloid deposits associated with Alzheimer disease (AD) provides doctors with useful information on treatment and further testing for patients with cognitive impairment, according to a study published online by the journal Alzheimer Disease & Associated Disorders. The journal is published by Lippincott Williams & Wilkins, a part ofWolters Kluwer Health. [...]

Early Diagnosis And Treatment Offered By New Tools For Alzheimer’s

Curtailing the imminent rise in Alzheimer’s disease (AD) will require early, accurate diagnostic tests and treatments, and researchers are closer to achieving these two goals. New findings in medical imaging, molecular analysis of neurological diseases, and development of treatments using mouse models were presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience [...]