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Research on yeast leads to evidence in key process of chromosome length – Findings could shed light on cancer, aging

Researchers at the Johns Hopkins University have found molecular evidence of how a biochemical process controls the lengths of protective chromosome tips, a potentially significant step in ultimately understanding cancer growth and aging. In a paper recently published as the cover story in the online journal eLife, biologist David C. Zappulla and graduate student Evan [...]

Yeast protein network could provide insights into human obesity

A team of biologists and a mathematician have identified and characterized a network composed of 94 proteins that work together to regulate fat storage in yeast. The “fatter” yeast cells that have had SNF4 knocked out. The larger fat droplets are colored green. Credit:Courtesy of Patrick Arpp/Caltech __SOURCEFROM__ The paper is entitled “Experimental and Computational [...]

Scientists reveal why beer tastes good to us and to flies

Beer yeasts produce chemicals that mimic the aroma of fruits in order to attract flies that can transport the yeast cells to new niches, report scientists from VIB, KU Leuven and NERF in the reputed journal Cell Reports. Interestingly, these volatile compounds are also essential for the flavor of beverages such as beer and wine. [...]

Genetic clues on drug response provided by yeast

Why do people respond differently to the same drug? For the first time, researchers have untangled genetic and environmental factors related to drug reactions, bringing us a step closer to predicting how a drug will affect us. Researchers at the University of British Columbia exposed 6,000 strains of yeast to 3,000 drugs. Yeast strains were [...]

A New Level Of Variation In Messenger RNAs Exposed

Like musicians in an orchestra who have the same musical score but start and finish playing at different intervals, cells with the same genes start and finish transcribing them at different points in the genome. For the first time, researchers at EMBL have described the striking diversity of messenger RNAs (mRNAs) that such start and [...]