Mice eat less when their hepatic glucose stores are high.
“We have to find treatments to increase hepatic glucose because of its positive effect in diabetes and obesity,” says Joan Guinovart, head of the study published in Diabetes.
ample from mouse liver. A high glycogen content (pink) suppresses appetite and improves the management of diabetes and obesity.
Credit: Image: I López-Soldado, IRB Barcelona
This study has been funded by the Ministerio de Economía y Competitividad and by the CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), a network to which the lab headed by Joan Guinovart – also senior professor at the University of Barcelona – belongs.
Iliana López-Soldado, Delia Zafra, Jordi Duran, Anna Adrover, Joaquim Calbó, Joan J. Guinovart
Diabetes. 2014 Oct 2. doi:10.2337/db14-0728