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Tracking information flow within the brain using ultra-precise magnetic resonance imaging

The continuously collects information. However, we have only basic knowledge of how new experiences are converted into lasting memories. Now, an international team led by researchers of the University of Magdeburg and the (DZNE) has successfully determined the location, where memories are generated with a level of precision never achieved before. The team was able to pinpoint this location down to specific circuits of the human brain. To this end the scientists used a particularly accurate type of (MRI) technology. The researchers hope that the results and method of their study might be able to assist in acquiring a better understanding of the effects Alzheimer’s disease has on the brain. The science journal “” reports on their findings.

[Magnetic resonance imaging provides insights into the brain]
Magnetic resonance imaging provides insights into the brain
Credit: DZNE/Guido Hennes


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This work was supported by the Deutsche Forschungsgemeinschaft (DFG), SFB 779-TP A07.

Original publication: Laminar activity in the hippocampus and entorhinal cortex related to novelty and episodic encoding. Anne Maass, Hartmut Schütze, Oliver Speck, Andrew Yonelinas, Claus Tempelmann, Hans-Jochen Heinze, David Berron, Arturo Cardenas-Blanco, Kay H. Brodersen, Klaas Enno Stephan, Emrah Düzel. Nature Communications, 2014, doi: 10.1038/ncomms6547

DZNE – German Center for Neurodegenerative Diseases