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Unlikely pairing – an antidepressant plus dye – yields tumor-targeting tool

Scientists combine molecules to create a drug that finds and suppresses prostate cancer in mice

Prostate Tumors
A near-infrared dye targets tumors in a mouse.
Credit:Jean Shih / USC


The research was done in collaboration with Jason Boyang Wu, , John Gallagher, , Leland W.K. Chung and Haiyen Zhau.

Funding came from the , ; the Boyd and ; NIH/National Cancer Center Institute; the Board of Governors Endowed Cancer Chair and the Margaret E. Early Award.

Monoamine Oxidase A Inhibitor–Near-Infrared Dye Conjugate Reduces Prostate Tumor Growth. J. Am. Chem. Soc., Article ASAP DOI: 10.1021/ja512613j Publication Date (Web): January 13, 2015

University of Southern California