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USC study shows how skeletal stem cells form the blueprint of the face

Timing is everything when it comes to the development of the vertebrate face. In a new study published in PLOS Genetics, USC Stem Cell researcher Lindsey Barske from the laboratory of Gage Crump and her colleagues identify the roles of key molecular signals that control this critical timing.

Zebrafish Head Skeleton
A three-day-old zebrafish head skeleton with newly differentiated cartilage cells (magenta) emerges from a pool of skeletal progenitor cells (green).
Credit: Lindsey Barske/Crump Lab