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Vaccine Delivery By Inhilation Instead Of By Injection?

In addition to the obvious benefit of eliminating the need for an injection, new methods via the lungs offer particular advantages for protecting against that enter the body through the respiratory track. A comprehensive review article that presents the current status, challenges, and opportunities of pulmonary is published in and Pulmonary Drug Delivery, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free online on the Journal of Aerosol Medicine and Pulmonary Drug Delivery* website.

In “Pulmonary Vaccine Delivery: A Realistic Approach*?” and coauthors from and and the Environment (Bilthoven), The Netherlands, describe the unique physiology and immune responsiveness of the respiratory track that make pulmonary vaccine delivery such an attractive alternative to traditional injections. Although pulmonary vaccination is still a young field, with much more research needed, evidence suggests administration of a vaccine to the lungs can induce a local immune response more effectively than conventional types of vaccine delivery, in addition to stimulating antibody production throughout the body. This could be especially important for combating pathogens that cause pulmonary diseases.

“The lung is an immunologic powerhouse that remains largely unexplored. Theoretically we should be able to avoid needles and simply inhale our vaccines,” says Editor-in-Chief Gerald C. Smaldone, MD, PhD, Professor and Chief, Division of Pulmonary and Critical Care Medicine at SUNY-Stony Brook.


* http://www.liebertpub.com/jamp


Mary Ann Liebert, Inc./Genetic Engineering News