3 days popular7 days popular1 month popular3 months popular

Yeast are first cells known to cure themselves of prions

Yeast cells can sometimes reverse the and clumping associated with diseases such as Alzheimer’s, according to new research from the .

[Yeast Cells Can Clear Amyloid]
When colonies of baker’s yeast cells that contain clumped (colonies of on left) are stressed by high temperatures, some can convert the aggregated to the non-clumping form of the protein (red cells in the colonies the right).
Credit: Serio laboratory/ University of Arizona molecular and cellular biology


Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing

DOI: http://dx.doi.org/10.7554/eLife.04288 Published December 9, 2014

University of Arizona