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Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer's disease

Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer’s disease

Alzheimer’s illness (AD) is a progressive neurodegenerative dysfunction that results in dementia and behavioral adjustments. Extracellular deposition of amyloid plaques (Aβ) and intracellular deposition of neurofibrillary tangles in neurons are the foremost pathogenicities of AD. Nevertheless, medicine concentrating on these therapeutic targets should not efficient. Subsequently, novel targets for the remedy of AD urgently should […]