Reworking development factor-beta 1 (TGF-β1), a pro-fibrotic tumour-derived issue promotes fibroblast differentiation within the tumour microenvironment and is believed to contribute to the event of pro-tumourigenic cancer-associated fibroblasts (CAFs) by selling myofibroblast differentiation. miRNA dysregulation has been demonstrated in myofibroblast transdifferentiation and CAF activation, nevertheless, their expression varies amongst cell varieties and with the tactic of […]
![Myofibroblast transdifferentiation is associated with changes in cellular and extracellular vesicle miRNA abundance](https://www.todaytopics.com/yt/uploads/2021/11/7u.png)