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Expectations may not match reality among cancer patients in some early phase clinical trials

In a study of cancer patients considering whether they should participate in phase I clinical trials, a high percentage were willing to participate after discussions with clinical staff, but nearly half thought that their tumors would shrink, which is much higher than what is realistically achieved. Published early online in CANCER, a peer-reviewed journal of [...]

Newly discovered immune cell type protects against lung infections during chemotherapy

St. Jude Children’s Research Hospital investigators have identified a new form of an immune cell that protected mice from life-threatening lung infections under conditions that mimic cancer chemotherapy. The research appears online today in the scientific journal Proceedings of the National Academy of Sciences (PNAS). “We have identified a new form of housekeeping macrophage in [...]

Unique molecular atlas of pancreas produced

Researchers at Karolinska Institutet have managed to produce the first molecular map of the genes that are active in the various cells of the human pancreas. They have also revealed differences in genetic activity between people with type 2 diabetes and healthy controls. The study, which is published in Cell Metabolism, was conducted in the [...]

Nearly one-third of unnecessary endoscopies could be avoided with faeces blood test

The number of patients referred to the hospital for an unnecessary endoscopy could be cut by nearly a third if an additional test that can be carried out by a GP could be incorporated, according to new research published in the open access journal BMC Medicine. This new diagnostic strategy for patients suspected of serious [...]

Vitamin B levels during pregnancy linked to eczema risk in child

Infants whose mothers had a higher level of a particular type of vitamin B during pregnancy have a lower risk of eczema at age 12 months, new Southampton research has shown. The study from the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, is the first to link maternal serum levels of nicotinamide, a [...]