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Charting a molecular map of the brain: A catalogue of dozens of new neuronal subtypes in the hypothalamus

The human brain is made up of billions of cells. We do not know the identity or exact function of countless thousands of them since comprehensive efforts to catalogue neurons have just recently begun. Studying these many still unidentified cells is an important “hot-spot” in frontier brain research since it offers the discovery of new [...]

Obesity-associated protein could be linked to leukemia development

Cancer researchers at the University of Cincinnati (UC) College of Medicine have found an obesity-associated protein’s role in leukemia development and drug response which could lead to more effective therapies for the illness. The study, which will be published online edition of Cancer Cell and led by Jianjun Chen, PhD, associate professor in the Department [...]

Hormone concentrations in young mammals predict trade-offs later in life

Early development after birth can have profound effects on survival and reproduction. Now new research suggests that concentrations of a hormone associated with growth and aging in humans can be used to predict growth, reproduction, and lifespan in a population of wild animals. Researchers studying spotted hyenas found that juvenile concentrations of insulin-like growth factor-1 [...]

Gelatin supplements, good for your joints?

A new study from Keith Baar’s Functional Molecular Biology Laboratory at the UC Davis College of Biological Sciences and the Australian Institute of Sport suggests that consuming a gelatin supplement, plus a burst of intensive exercise, can help build ligaments, tendons and bones. The study is published in the American Journal of Clinical Nutrition. Connective [...]

New insight for developing more effective drugs to combat inflammatory bowel disease

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn’s disease and ulcerative colitis. It is commonly treated with one of several available biological drugs that block an inflammatory molecule called Tumor Necrosis Factor Alpha (TNF-alpha), but not everybody is helped by this treatment. New research by a team of [...]