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Researchers describe how tumors recruit and use stem cells to support tumor growth and progression

A new study has identified a mechanism used by tumors to recruit stem cells from bone and convert them into cancer-associated fibroblasts (CAFs) that facilitate tumor progression. This work, which pinpoints the specific biochemical pathways and cell signaling molecules involved in these processes, could lead to new therapeutic targets for suppressing tumor growth, as discussed [...]

Genetic hallmarks of acute lymphoblastic leukemia subtype uncovered

St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project team identifies genetic changes underlying a type of B-precursor acute lymphoblastic leukemia An international team of researchers from the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) and the Children’s Oncology Group (COG) has identified the genetic changes [...]

Elderly may face increased dementia risk after a disaster

Elderly people who were uprooted from damaged or destroyed homes and who lost touch with their neighbors after the 2011 tsunami in Japan were more likely to experience increased symptoms of dementia than those who were able to stay in their homes, according to a new study from Harvard T.H. Chan School of Public Health. [...]

Taking meds after heart procedures may boost trouble-free survival rate

Regardless of heart procedure, patients who adhered to prescribed medication were more than twice as likely to have event-free rates of survival. Heart bypass patients appeared to be more resistant than PCI patients to the negative effects of not taking prescribed medication. Not taking prescribed medications is common among patients who had either bypass surgery [...]

Study indicates that advances in precision medicine have improved breast cancer treatment

A new study examines how one early example of precision medicine – tumor genome testing – is being used in women with breast cancer to reduce overtreatment and maximize the benefits of chemotherapy. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study found that physician recommendations and final treatment [...]